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Showing posts from May, 2018

Painless real-time proteomics may one day speed up cancer surgery

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Fournier, a professor at the University of Lille and co-director of a proteomics center of INSERM, the French national institute of health. In Her laboratory, she has worked for several years on a device. It was called “Spider Mass” that will enable the surgeons to identify markers of cancer in a living patient's tissue, during an operation. Surgery to remove a primary tumor and after some healthy surrounding tissue are removed, Although this process will help for preventing recurrence of the cancer, it can add up to 45 risky minutes under anesthesia. Fournier's device uses mass spectrometry method, which measures the mass of molecules from complex mixtures. But turning an in vivo tissue sample into gas phase ions for measurements can be a challenge. Until now, no one knew how to extract ions from living tissues without doing harm. Riffing on MALDI, it is an ionization strategy that uses a carrier molecule mixed with the analyte of interest; then they decided to ...

Effects of Computerized Physician Order Entry and Clinical Decision Support Systems on Medication Safety

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Medications are the most common treatment used in healthcare around the world. When used safely and appropriately, they contribute to significant improvements in the health and well-being of patients. Iatrogenic injuries related to medications are common, costly, and clinically significant. Computerized physician order entry (CPOE) and clinical decision support systems (CDSSs) may reduce medication error rates. They have undergone several clinical trial methods. Methods Adapted: The researchers Rainu Kaushal, MD, MPH; Kaveh G. Shojania, MD; David W. Bates, MD, MSc, were identified clinical trials that evaluated the effects of Computerized physician order entry (CPOE) and clinical decision support systems (CDSSs) on medication safety by electronically searching MEDLINE and the Cochrane Library and by manually searching the bibliographies of retrieved articles. Studies were included for systematic review if the design was a randomized controlled trial, a nonrandomized cont...

A Comprehensive Approach for Mycetoma Management

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Mycetoma is a severe infection of skin and it can also cause some chronic infection to the subcutaneous tissue. The condition was first described in the region of Madura in India where the disease was first identified. Mycetoma is also a tropical disease; it can cause severe disfigurement and disability if it is not treated early. Mycetoma can be caused by any of 70 fungi or actinomycetes bacteria. In all cases, chronic and progressive infection and inflammation cause masses under the skin which can spread to deeper structures including bone. Sudan has one of the highest rates of mycetoma endemicity in the world, though the disease is found throughout the tropics and subtropics. Mycetoma patients are often hindered from timely and appropriate treatment by financial limitations and geographic remoteness from regional health facilities. In this work had done by Ahmed Fahal, from the University of Khartoum, Sudan, and his colleagues at the Myectoma Research Centre (MRC) a...

Substance in Traditional Chinese Medicine – can cause cardiac arrhythmia

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Traditional Chinese medicine is a style of medicine that built on a foundation of more than 2,500 years of Chinese medical practice. It includes various forms of natural and herbal medicine, but recently it was influenced by modern Western medicine. TCM is widely used in China and is becoming increasingly popular and recognized worldwide. A medicinal plant which is frequently used in Traditional Chinese Medicine (TCM) is -- Evodia rutaecarpa – that contains substances can cause cardiac arrhythmia. It was found by the researchers from Universities of Basel, Vienna. The plant Extracts from Evodia rutaecarpa that are used in Traditional Chinese Medicine for a variety of symptoms, such as headaches and vomiting sensation as well as menstrual complaints and ulcers. The Professor Matthias Hamburger from the Department of Pharmaceutical Sciences at the University of Basel who discovered the effect of Evodia plant extracts with the help of pharmacologists and toxicologis...